Canopy temperature based regression models were developed for the prediction of grain yield of wheat. During the reproductive phase, all the canopy temperature based indices viz., canopy temperature (Tc ), average canopy minus air temperature (Tc -Ta ) and summation stress degree days (SDD) showed a negative and significant relationship explaining 71-87% variation in grain yield. These findings signify an ample scope of mid day canopy temperature as a possible tool for monitoring plant water status and grain yield prediction.