The insect-pests infestation in cucumber leads to severe injury to its’ vegetative parts and fruits by epilachna beetle, red pumpkin beetle, whitefly, pumpkin caterpillar, leaf minerand fruit fly. The present investigation was taken upduring 2014 and 2015 to study the population dynamics of prevailing six insect-pests of cucumber and its natural enemies inrelation to weather parameters.The correlation studies between insect pests and weather parameters revealed that the melon fruit fly (Bactrocera cucurbitae Coquillett), epilachna beetle (Epilachna vigintioctopunctata Fabricius), red pumpkin beetle (Aulacophora foveicollisLucas), whitefly (Bemisia tabaci Gennadius), pumpkin caterpillar (Diaphania indica Saunders) and leaf miner (Liriomyza trifolii Burgess) showed significant positive correlation with maximum and minimum temperature,whereas negative and nonsignificant correlation with relative humidity and rainfall. The natural enemies such ascoccinellids and spiders showed significant positive correlation with maximum and minimum temperature, and non significant negative correlation with relative humidity and rainfall. Sunshine hour showed positive correlation with all the insect pests and natural enemies except epilachna beetle.